{"id":434,"date":"2022-01-25T16:46:12","date_gmt":"2022-01-25T07:46:12","guid":{"rendered":"http:\/\/twins.twmu.ac.jp\/SFM\/journal\/?p=434"},"modified":"2023-03-03T15:48:50","modified_gmt":"2023-03-03T06:48:50","slug":"%e8%8a%b1%e7%b2%89%e3%82%92%e5%aa%92%e4%bd%93%e3%81%a8%e3%81%97%e3%81%9f%e3%82%a4%e3%83%b3%e3%83%95%e3%83%ab%e3%83%af%e3%82%af%e3%83%81%e3%83%b3%e6%8b%a1%e6%95%a3%e3%82%b7%e3%82%b9%e3%83%86%e3%83%a0","status":"publish","type":"post","link":"https:\/\/twins.twmu.ac.jp\/SFM\/journal\/archives\/434","title":{"rendered":"\u82b1\u7c89\u3092\u5a92\u4f53\u3068\u3057\u305f\u30a4\u30f3\u30d5\u30eb\u30ef\u30af\u30c1\u30f3\u62e1\u6563\u30b7\u30b9\u30c6\u30e0"},"content":{"rendered":"<p><strong>\uff11\uff0e\u80cc\u666f<\/strong><\/p><p><strong>\uff11\uff0e\uff11\uff0e\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a3\u30eb\u30b9\u306e\u8105\u5a01<\/strong><\/p><p>\u3000\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306b\u611f\u67d3\u3059\u308b\u3068\u6570\u65e5\u7a0b\u5ea6\u306e\u6f5c\u4f0f\u671f\u9593\u3092\u7d4c\u3066\u767a\u75c7\u3057\u300138\u5ea6\u4ee5\u4e0a\u306e\u9ad8\u71b1\u3001\u982d\u75db\u3001\u5168\u8eab\u306e\u5026\u6020\u611f\u3001\u7b4b\u8089\u75db\u30fb\u95a2\u7bc0\u75db\u3084\u54b3\u30fb\u9f3b\u6c41\u306a\u3069\u306e\u75c7\u72b6\u304c\u73fe\u308c\u308b\u3002\u5b63\u7bc0\u6027\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u3067\u3042\u308c\u3070\u901a\u5e381\u9031\u9593\u7a0b\u5ea6\u3067\u56de\u5fa9\u3059\u308b\u304c\u3001\u547c\u5438\u5668\u3084\u5fc3\u81d3\u306b\u75be\u60a3\u3092\u62b1\u3048\u308b\u4eba\u3084\u9ad8\u9f62\u8005\u3067\u306f\u91cd\u75c7\u5316\u3057\u3084\u3059\u304f\u3001\u6700\u60aa\u306e\u5834\u5408\u6b7b\u306b\u81f3\u308b\u3002<\/p><p>\u3000\u5b63\u7bc0\u6027\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306e\u5834\u5408\u3001\u8105\u5a01\u3068\u306a\u308b\u306e\u306f\u81f4\u6b7b\u7387\u3067\u306f\u306a\u304f\u305d\u306e\u611f\u67d3\u80fd\u529b\u306e\u9ad8\u3055\u3067\u3042\u308b\u3002\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u611f\u67d3\u8005\u304c\u54b3\u3084\u304f\u3057\u3083\u307f\u3092\u3059\u308b\u3068\u53e3\u304b\u3089\u7d045-10\u4e07\u500b\u306e\u98db\u6cab\u304c\u6392\u51fa\u3055\u308c\u3001\u540c\u6642\u306b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a3\u30eb\u30b9\u3082\u98db\u6563\u3059\u308b\u3002\u305d\u308c\u3092\u4ed6\u8005\u304c\u5438\u3044\u8fbc\u3080\u3068\u3001\u30a6\u30a3\u30eb\u30b9\u7c92\u5b50\u304c\u9f3b\u7c98\u819c\u3084\u54bd\u5589\u982d\u7c98\u819c\u4e0a\u306e\u7d30\u80de\u8868\u9762\u306b\u5438\u7740\u3055\u308c\u3001\u30a8\u30f3\u30c9\u30b5\u30a4\u30c8\u30fc\u30b7\u30b9\u3092\u7d4c\u3066\u7d30\u80de\u5185\u306b\u53d6\u308a\u8fbc\u307e\u308c\u308b\u3002\u305d\u3057\u3066\u819c\u878d\u5408\u3092\u7d4c\u3066\u8131\u6bbb\u3092\u884c\u3044\u3001RNA\u30bf\u30f3\u30d1\u30af\u8cea\u8907\u5408\u4f53\u3092\u7d30\u80de\u8cea\u306e\u4e2d\u306b\u653e\u51fa\u3002\u5bbf\u4e3b\u7d30\u80de\u306e\u5c0f\u5668\u5b98\u3092\u4f7f\u3063\u3066\u81ea\u8eab\u306eRNA\u306e\u92f3\u578b\u3092\u4f5c\u6210\u3057RNA\u3092\u8907\u88fd\u3059\u308b\u3002\u305d\u306e\u5f8c\u3001\u69d8\u3005\u306a\u69cb\u6210\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u5408\u6210\u3092\u884c\u3063\u305f\u5f8c\u3001\u30a6\u30a3\u30eb\u30b9\u306e\u5b50\u4f9b\u304c\u7523\u751f\u3055\u308c\u3001\u5bbf\u4e3b\u7d30\u80de\u304b\u3089\u904a\u96e2\u3059\u308b\u3002\u6700\u5f8c\u306b\u958b\u88c2\u3092\u884c\u3044\u5468\u8fba\u306e\u6b63\u5e38\u7d30\u80de\u306b\u611f\u67d3\u53ef\u80fd\u306a\u819c\u878d\u5408\u80fd\u3092\u6709\u3057\u305f\u5b50\u30a6\u30a3\u30eb\u30b9\u304c\u8a95\u751f\u3059\u308b\u3002\u3053\u308c\u3092\u4f53\u5185\u3067\u7e70\u308a\u8fd4\u3057\u3001\u6307\u6570\u95a2\u6570\u7684\u306b\u5897\u6b96\u3059\u308b<sup>1)<\/sup>\u3002\u3053\u306e\u3088\u3046\u306b\u98db\u6cab\u3084\u63a5\u89e6\u3092\u4ecb\u3057\u3066\u30d2\u30c8\u304b\u3089\u30d2\u30c8\u3078\u3068\u611f\u67d3\u3092\u7e70\u308a\u8fd4\u3059\u3002\u7c73\u56fdCDC\u306e\u7d71\u8a08\u306b\u3088\u308b\u3068\u3001\u3053\u306e\u611f\u67d3\u80fd\u529b\u306e\u9ad8\u3055\u306b\u3088\u308a\u7c73\u56fd\u3067\u306f\u6bce\u30b7\u30fc\u30ba\u30f3\u5e73\u57473,000\u4e07\u4eba\u304c\u5b63\u7bc0\u6027\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306b\u611f\u67d3\u3057\u3001\u305d\u306e\u3046\u3061\u7d0438,000\u4eba\u304c\u4ea1\u304f\u306a\u3063\u3066\u3044\u308b\u3068\u3055\u308c\u3066\u3044\u308b\u3002\u7279\u306b2017-8\u30b7\u30fc\u30ba\u30f3\u3067\u306f\u5b9f\u306b61,000\u4eba\u304c\u5b63\u7bc0\u6027\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u3067\u4ea1\u304f\u306a\u3063\u3066\u304a\u308a\u3001\u5f71\u97ff\u306f\u751a\u5927\u3067\u3042\u308b\u3002(\u56f3\uff11)<\/p><div 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class=\"fig\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-436 size-large\" src=\"http:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f32-1024x245.png\" alt=\"\" width=\"1024\" height=\"245\" srcset=\"https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f32-1024x245.png 1024w, https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f32-300x72.png 300w, https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f32-768x184.png 768w, https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f32.png 1890w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><div class=\"caption\"><strong>\u56f32. \u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306e\u4e9c\u578b\u306e\u7a2e\u985e\u3068A\u578b\u30a6\u30a3\u30eb\u30b9\u306e\u69cb\u9020<\/strong><\/div><\/div><p>&nbsp;<\/p><p><strong>\uff11\uff0e\uff12\uff0e\u73fe\u5728\u306e\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u30b7\u30b9\u30c6\u30e0\u306e\u9650\u754c<\/strong><\/p><p>\u3000\u5b63\u7bc0\u6027\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306e\u6d41\u884c\u3092\u6291\u3048\u308b\u305f\u3081\u306b\u3082\u3063\u3068\u3082\u6709\u52b9\u306a\u306e\u304c\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3067\u3042\u308b\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306f\u6bce\u5e74\u6d41\u884c\u3059\u308b\u30bf\u30a4\u30d7\u3084\u4e9c\u578b\u304c\u7570\u306a\u308b\u305f\u3081\u3001\u63a5\u7a2e\u3057\u305f\u30ef\u30af\u30c1\u30f3\u306e\u4e9c\u578b\u3068\u306e\u6574\u5408\u6027\u304c\u4f4e\u3044\u3068\u4e88\u9632\u52b9\u679c\u304c\u8584\u308c\u308b\u3002\u3088\u3063\u3066\u3001\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3057\u305f\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306b\u611f\u67d3\u3057\u3066\u3057\u307e\u3046\u30b1\u30fc\u30b9\u3082\u591a\u304f\u3001\u30ef\u30af\u30c1\u30f3\u306e\u52b9\u679c\u3092\u7591\u554f\u8996\u3059\u308b\u58f0\u3082\u5f37\u3044\u3002\u305d\u306e\u305f\u3081\u3001\u7c73\u56fd\u6c11\u306e\u4e88\u9632\u610f\u8b58\u306e\u4f4e\u3055\u306b\u76f8\u307e\u3063\u3066\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u7387\u304c\u9ad8\u307e\u3089\u306a\u3044\u306e\u304c\u73fe\u72b6\u3067\u3042\u308b\u3002\u5b9f\u969b\u3001\u7c73\u56fdCDC\u306b\u3088\u308a\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306e\u7121\u6599\u5316\u3084\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u8005\u306b\u30c9\u30e9\u30c3\u30b0\u30b9\u30c8\u30a2\u306e\u30af\u30fc\u30dd\u30f3\u914d\u5e03\u306a\u3069\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u7387\u3092\u4e0a\u3052\u308b\u69d8\u3005\u306a\u8a66\u307f\u304c\u7a4d\u6975\u7684\u306b\u53d6\u3089\u308c\u3066\u304d\u305f\u306b\u3082\u62d8\u308f\u3089\u305a\u30012018-19\u5e74\u30b7\u30fc\u30ba\u30f3\u306e\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u7387\u306f45.3%\u306b\u7559\u307e\u308a<sup>2)<\/sup>\u3001\u65e5\u672c\u306e\u63a5\u7a2e\u738749%\u3088\u308a\u3082\u4f4e\u3044\u72b6\u6cc1\u3068\u306a\u3063\u3066\u3044\u308b\u3002<\/p><p>&nbsp;<\/p><p><strong>\uff12\uff0e\u63d0\u6848<\/strong><\/p><p><strong>\u82b1\u7c89\u3092\u5a92\u4f53\u3068\u3057\u305f\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u4e0d\u6d3b\u5316\u6297\u539f\u306e\u62e1\u6563\u30b7\u30b9\u30c6\u30e0<\/strong><\/p><p>\u3000\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306b\u3088\u308b\u6b7b\u8005\u6570\u3092\u4f4e\u6e1b\u3059\u308b\u306b\u306f\u3001\u56fd\u6c11\u306e\u4e88\u9632\u610f\u8b58\u306b\u5de6\u53f3\u3055\u308c\u308b\u3053\u3068\u306a\u304f\u514d\u75ab\u3092\u91b8\u6210\u3059\u308b\u30b7\u30b9\u30c6\u30e0\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002\u305d\u3053\u3067\u6728\u3005\u306e\u82b1\u7c89\u4e0a\u306b\u3042\u3089\u3086\u308b\u4e9c\u578b\u306b\u5bfe\u3057\u6709\u52b9\u306a\u4ea4\u5dee\u6297\u4f53\u3092\u7523\u751f\u3059\u308b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u4e0d\u6d3b\u5316\u6297\u539f\u3092\u767a\u73fe\u3055\u305b\u3001\u82b1\u7c89\u304c\u4eba\u3005\u306b\u98db\u6765\u3059\u308b\u3053\u3068\u3067\u3001\u65e5\u5e38\u751f\u6d3b\u3092\u9001\u308b\u4e2d\u3067\u7121\u610f\u8b58\u306e\u3046\u3061\u306b\u96c6\u56e3\u514d\u75ab\u3092\u91b8\u6210\u3059\u308b\u30b7\u30b9\u30c6\u30e0\u3092\u63d0\u6848\u3059\u308b\u3002<\/p><p>&nbsp;<\/p><p><strong>\uff12\uff0e\uff11\uff0e\u690d\u7269\u82b1\u7c89\u4e0a\u306b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u6297\u539f\u3092\u767a\u73fe\u3059\u308b<\/strong><\/p><p>\u3000\u690d\u7269\u4e0a\u306b\u6297\u539f\u3092\u767a\u73fe\u3055\u305b\u30ef\u30af\u30c1\u30f3\u3068\u3057\u3066\u7528\u3044\u308b\u7814\u7a76\u306f\u3053\u308c\u307e\u3067\u3082\u5b9f\u65bd\u3055\u308c\u3001\u4e00\u5b9a\u306e\u6210\u679c\u3092\u6319\u3052\u3066\u3044\u308b\u30022007\u5e74\u3001\u91ce\u5730\u3089<sup>3)<\/sup>\u306f\u30b3\u30ec\u30e9\u6bd2\u7d20B\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u306eCTB\u3092\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u6280\u8853\u306b\u3088\u308a\u30a4\u30cd\u4e0a\u3067\u767a\u73fe\u3055\u305b\u3001\u7c73\u30d9\u30fc\u30b9\u306e\u7d4c\u53e3\u30ef\u30af\u30c1\u30f3\u3092\u958b\u767a\u3057\u3001\u30de\u30a6\u30b9\u306b\u7d4c\u53e3\u6295\u4e0e\u3059\u308b\u3053\u3068\u3067\u3001CTB\u7279\u7570\u7684\u306a\u8840\u6e05IgG\u53ca\u3073\u7c98\u819cIgA\u6297\u4f53\u306e\u78ba\u8a8d\u306b\u6210\u529f\u3057\u305f (\u56f33)\u3002<\/p><div class=\"fig\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-437\" src=\"http:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f33-1024x484.png\" alt=\"\" width=\"512\" height=\"242\" srcset=\"https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f33-1024x484.png 1024w, https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f33-300x142.png 300w, https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f33-768x363.png 768w, https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f33.png 1095w\" sizes=\"(max-width: 512px) 100vw, 512px\" \/><div class=\"caption\"><strong>\u56f33. CTB\u767a\u73fe\u3057\u305f\u30b3\u30e1\u3092\u30de\u30a6\u30b9\u306b\u7d4c\u53e3\u6295\u4e0e\u3057\u305f\u5b9f\u9a13\u7d50\u679c<\/strong><\/div><div>\u00a0<\/div><\/div><p>\u3000\u307e\u305f\u3001\u82b1\u5349\u7523\u696d\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3057\u305f\u8fb2\u5b66\u306e\u5206\u91ce\u3067\u306f\u3001\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u306b\u3088\u308a\u65b0\u3057\u3044\u8272\u3001\u5f62\u3092\u6301\u3064\u65b0\u7a2e\u306e\u82b1\u5f01\u3092\u4f5c\u6210\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u3001\u7d44\u307f\u63db\u3048\u907a\u4f1d\u5b50\u3092\u82b1\u5f01\u7279\u7570\u7684\u306b\u767a\u73fe\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306e\u7814\u7a76\u304c\u306a\u3055\u308c\u3066\u304d\u305f\u30022015\u5e74\u3001\u6771\u3089\u306e\u7814\u7a76<sup>4)<\/sup>\u306b\u304a\u3044\u3066\u3001\u30a2\u30b5\u30ac\u30aa\u306eInMYB1\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u3068GUS\u67d3\u8272\u907a\u4f1d\u5b50\u3092\u7d44\u5408\u305b\u3001GUS\u67d3\u8272\u30b9\u30dd\u30c3\u30c8\u304c\u767a\u73fe\u3057\u305f\u7b87\u6240\u3092\u89b3\u5bdf\u3059\u308b\u3053\u3068\u3067\u3001InMYB1\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u304c\u82b1\u5f01\u7279\u7570\u7684\u306b\u907a\u4f1d\u5b50\u3092\u767a\u73fe\u3055\u305b\u308b\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002\u307e\u305f\u3001\u672c\u5831\u544a\u306e\u4e2d\u3067\u3001\u83ca\u306eCmCCD4a-5\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u304c\u82b1\u7c89\u3068\u82b1\u5f01\u3067\u6700\u3082\u5f37\u3044\u6d3b\u6027\u3092\u793a\u3059\u3053\u3068\u304c\u8ff0\u3079\u3089\u308c\u3066\u3044\u308b\u3002<\/p><p>\u3000\u4e0a\u8a18\u7814\u7a76\u306b\u306a\u3089\u3044\u3001\u6728\u3005\u306e\u82b1\u7c89\u7279\u7570\u7684\u306b\u8d77\u52d5\u3059\u308b\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u3092\u7279\u5b9a\u3057\u3001\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u3092\u884c\u3046\u969b\u306b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u4e0d\u6d3b\u5316\u6297\u539f\u306e\u907a\u4f1d\u5b50\u3068\u4e00\u7dd2\u306b\u7d44\u307f\u8fbc\u3080\u3053\u3068\u3067\u3001\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u4e0d\u6d3b\u5316\u6297\u539f\u3092\u6728\u3005\u306e\u82b1\u7c89\u4e0a\u306b\u7279\u7570\u7684\u306b\u767a\u73fe\u3055\u305b\u308b\u3053\u3068\u304c\u53ef\u80fd\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/p><p>&nbsp;<\/p><p><strong>\uff12\uff0e\uff12\uff0e\u3042\u3089\u3086\u308b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u4e9c\u578b\u3092\u30ab\u30d0\u30fc\u3059\u308b\u4ea4\u5dee\u6297\u4f53\u3092\u8a98\u5c0e\u3059\u308b\u6297\u539f<\/strong><\/p><p>\u3000\u3053\u308c\u307e\u3067\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306e\u30ef\u30af\u30c1\u30f3\u306f\u7570\u306a\u308b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u4e9c\u578b\u3078\u306e\u6709\u52b9\u6027\u304c\u4f4e\u3044\u3068\u3055\u308c\u3066\u304d\u305f\u3002\u3057\u304b\u3057\u306a\u304c\u30892019\u5e74\u3001\u5b89\u9054\u3089<sup>5)<\/sup>\u306b\u3088\u308a\u3001\u30d2\u30c8\u306b\u306f\u3042\u3089\u3086\u308b\u4e9c\u578b\u306b\u5bfe\u3057\u3066\u6709\u52b9\u306a\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u4ea4\u5dee\u9632\u5fa1\u6297\u4f53\u304c\u5099\u308f\u3063\u3066\u304a\u308a\u3001\u30d2\u30c8\u5316\u30de\u30a6\u30b9\u3092\u7528\u3044\u305f\u7814\u7a76\u306b\u304a\u3044\u3066\u3001\u6297\u539f\u3092\u9178\u6027\u51e6\u7406\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u4ea4\u5dee\u9632\u5fa1\u6297\u4f53\u306e\u8a98\u5c0e\u304c\u53ef\u80fd\u306b\u306a\u308b\u3068\u3044\u3046\u7814\u7a76\u7d50\u679c\u304c\u793a\u3055\u308c\u305f(\u56f34)\u3002<\/p><div class=\"fig\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-438\" src=\"http:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f34-233x300.png\" alt=\"\" width=\"233\" height=\"300\" srcset=\"https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f34-233x300.png 233w, https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f34.png 290w\" sizes=\"(max-width: 233px) 100vw, 233px\" \/><div class=\"caption\"><strong>\u56f34. \u901a\u5e38\u6297\u539f\u3068\u6539\u5909\u578b\u6297\u539f\u306e\u6297\u4f53\u6fc3\u5ea6\u306e\u6bd4\u8f03<\/strong><\/div><div>\u00a0<\/div><\/div><p>\u3000\u901a\u5e38\u306e\u30d8\u30de\u30b0\u30eb\u30c1\u30cb\u30f3\u6297\u539f\u3067\u306f\u4ea4\u5dee\u9632\u5fa1\u6027B\u7d30\u80de\u304c\u8a8d\u8b58\u3059\u308bLAH\u3068\u3044\u3046\u30a8\u30d4\u30c8\u30fc\u30d7\u304c\u96a0\u308c\u3066\u304a\u308a\u3001\u4ea4\u5dee\u9632\u5fa1\u6027\u6297\u4f53\u304c\u8a98\u5c0e\u3055\u308c\u306b\u304f\u3044\u304c\u3001\u30d8\u30de\u30b0\u30eb\u30c1\u30cb\u30f3\u6297\u539f\u3092PH5.0\u306e\u74b0\u5883\u4e0b\u3067\u9178\u6027\u51e6\u7406\u3092\u65bd\u3059\u3068\u3001LAH\u304c\u9732\u51fa\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u4ea4\u5dee\u9632\u5fa1\u6027B\u7d30\u80de\u304c\u7d50\u5408\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\uff08\u56f35\uff09\u3001\u4ea4\u5dee\u9632\u5fa1\u6027\u6297\u4f53\u304c\u8a98\u5c0e\u3055\u308c\u308b\u3053\u3068\u304c\u5224\u660e\u3057\u305f\u3002<\/p><div class=\"fig\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-439\" src=\"http:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f35.png\" alt=\"\" width=\"443\" height=\"300\" srcset=\"https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f35.png 602w, https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f35-300x203.png 300w\" sizes=\"(max-width: 443px) 100vw, 443px\" \/><div class=\"caption\"><strong>\u56f35. \u9178\u6027\u51e6\u7406\u306b\u3088\u308b\u30a8\u30d4\u30c8\u30fc\u30d7\u306e\u9732\u51fa<\/strong><\/div><div>\u00a0<\/div><\/div><p>\u3000\u3053\u306e\u6539\u5909\u578b\u30d8\u30de\u30b0\u30eb\u30c1\u30cb\u30f3\u6297\u539f\u3092\u7528\u3044\u308b\u3053\u3068\u3067\u3001\u69d8\u3005\u306a\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u4e9c\u578b\u3092\u30ab\u30d0\u30fc\u3057\u3001\u5b63\u7bc0\u6027\u3001\u9ce5\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u5171\u306b\u6709\u52b9\u306a\u30ef\u30af\u30c1\u30f3\u5b9f\u73fe\u306e\u53ef\u80fd\u6027\u304c\u51fa\u3066\u304d\u305f\u3002<\/p><p>\u3000\u672c\u63d0\u6848\u306b\u304a\u3044\u3066\u3001\u6297\u539f\u306e\u9178\u6027\u51e6\u7406\u306f\u964d\u96e8\u306b\u3088\u3063\u3066\u306a\u3055\u308c\u308b\u3053\u3068\u3092\u60f3\u5b9a\u3057\u3066\u3044\u308b\u3002\u7c73\u56fd\u3084\u65e5\u672c\u3067\u306f\u8fd1\u5e74\u9178\u6027\u96e8\u306e\u5f71\u97ff\u3067\u96e8\u6c34\u306ePH\u306f\u5e73\u57474.8\u3068\u306a\u3063\u3066\u3044\u308b\u3002\u82b1\u7c89\u4e0a\u306b\u901a\u5e38\u306e\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u4e0d\u6d3b\u5316\u6297\u539f\u3092\u767a\u73fe\u3055\u305b\u308b\u3068\u3001\u9178\u6027\u96e8\u306b\u3088\u308a\u6297\u539f\u304c\u9178\u6027\u5316\u3055\u308c\u3001LAH\u304c\u9732\u51fa\u3057\u305f\u6539\u5909\u578b\u6297\u539f\u306b\u5909\u8c8c\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u308b\u3002\u305d\u306e\u6297\u539f\u3092\u6709\u3057\u305f\u82b1\u7c89\u304c\u98a8\u306b\u4e57\u308a\u4eba\u3005\u306e\u5143\u306b\u5c4a\u304d\u3001\u4eba\u3005\u306e\u9f3b\u3084\u54bd\u5589\u982d\u306e\u7c98\u819c\u4e0a\u306b\u4ed8\u7740\u3059\u308b\u3053\u3068\u3067\u4ea4\u5dee\u9632\u5fa1\u6297\u4f53\u3092\u91b8\u6210\u3059\u308b\u3002<\/p><p>\u3000\u4ee5\u4e0b\u306b\u672c\u63d0\u6848\u306e\u5168\u4f53\u6982\u7565\u56f3\u3092\u793a\u3059\u3002<\/p><div class=\"fig\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-440\" src=\"http:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f36-1024x550.png\" alt=\"\" width=\"744\" height=\"400\" srcset=\"https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f36-1024x550.png 1024w, https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f36-300x161.png 300w, https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f36-768x413.png 768w, https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f36.png 1756w\" sizes=\"(max-width: 744px) 100vw, 744px\" \/><div class=\"caption\"><strong>\u56f36. \u672c\u30b7\u30b9\u30c6\u30e0\u306e\u5168\u4f53\u6982\u7565<\/strong><\/div><\/div><p>&nbsp;<\/p><p><strong>\uff13\uff0e\u8ab2\u984c\u3068\u5c55\u671b<\/strong><\/p><p><strong>\uff13\uff0e\uff11\u3000\u8ab2\u984c\u2460\u3000\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u30b7\u30e7\u30c3\u30af\u306e\u30ea\u30b9\u30af<\/strong><\/p><p>\u3000\u4e0d\u7279\u5b9a\u591a\u6570\u306e\u4eba\u306b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u6297\u539f\u3092\u6563\u5e03\u3059\u308b\u305f\u3081\u3001\u514d\u75ab\u75be\u60a3\u7b49\u306e\u4eba\u3005\u3078\u306e\u5f71\u97ff\u3092\u8003\u616e\u3059\u308b\u3068\u3001\u4e0d\u6d3b\u5316\u6297\u539f\u306e\u4f7f\u7528\u304c\u9069\u5207\u3068\u8003\u3048\u3089\u308c\u308b\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u4e0d\u6d3b\u5316\u6297\u539f\u3092\u4f7f\u7528\u3057\u305f\u3068\u3057\u3066\u3082\u3001\u6db2\u6027\u514d\u75ab\u3092\u8a98\u5c0e\u3057\u3001\u4ea4\u5dee\u9632\u5fa1\u6297\u4f53\u306e\u7523\u751f\u3092\u671f\u5f85\u3059\u308b\u305f\u3081\u3001\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u30b7\u30e7\u30c3\u30af\u3078\u306e\u914d\u616e\u304c\u5fc5\u9808\u3067\u3042\u308b\u3002\u30ea\u30b9\u30af\u3092\u6975\u529b\u4f4e\u6e1b\u3059\u308b\u305f\u3081\u3001\u6297\u539f\u6563\u5e03\u3092\u9ad8\u6fc3\u5ea6\u306b\u3057\u3066\u77ed\u671f\u9593\u3067\u96c6\u56e3\u514d\u75ab\u3092\u91b8\u6210\u3059\u308b\u72d9\u3044\u3067\u306f\u306a\u304f\u3001\u6975\u529b\u6297\u539f\u306e\u6563\u5e03\u6fc3\u5ea6\u3092\u4f4e\u304f\u6291\u3048\u3001\u6570\u5e74\u898f\u6a21\u3068\u3044\u3063\u305f\u4e2d\u9577\u671f\u7684\u30b9\u30d1\u30f3\u3067\u5f90\u3005\u306b\u96c6\u56e3\u514d\u75ab\u3092\u91b8\u6210\u3059\u308b\u72d9\u3044\u306b\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002<\/p><p><strong>\u00a0<\/strong><\/p><p><strong>\uff13\uff0e\uff12\u3000\u8ab2\u984c\u2461\u3000\u30b7\u30b9\u30c6\u30e0\u30d7\u30ed\u30c8\u30bf\u30a4\u30d7\u306e\u4f5c\u6210\u3068\u81e8\u5e8a\u8a66\u9a13\u306e\u9577\u671f\u5316<\/strong><\/p><p><strong>\u3000<\/strong>\u30b7\u30b9\u30c6\u30e0\u306e\u30d7\u30ed\u30c8\u30bf\u30a4\u30d7\u3092\u4f5c\u6210\u3059\u308b\u904e\u7a0b\u306b\u304a\u3044\u3066\u3001\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u3092\u5b9f\u65bd\u3057\u3066\u304b\u3089\u3001\u6728\u3005\u306e\u6210\u9577\u3068\u6297\u539f\u306e\u767a\u73fe\u306b\u6642\u9593\u3092\u8981\u3059\u308b\u3053\u3068\u3084\u3001\u30d2\u30c8\u304c\u82b1\u7c89\u4e0a\u306e\u6297\u539f\u3092\u5438\u5165\u3057\u305f\u969b\u306e\u4e2d\u9577\u671f\u7684\u5f71\u97ff\u3092\u89b3\u5bdf\u3059\u308b\u306e\u306b\u6642\u9593\u3092\u8981\u3059\u308b\u305f\u3081\u3001\u30b7\u30b9\u30c6\u30e0\u306e\u904b\u7528\u307e\u3067\u591a\u5927\u306a\u6642\u9593\u3092\u8981\u3059\u308b\u3053\u3068\u304c\u4e88\u60f3\u3055\u308c\u308b\u3002\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u306e\u969b\u306b\u3001\u6728\u3005\u306e\u6210\u9577\u901f\u5ea6\u3092\u901f\u3081\u308b\u907a\u4f1d\u5b50\u3092\u540c\u6642\u306b\u7d44\u307f\u8fbc\u307f\u3001\u30d7\u30ed\u30c8\u30bf\u30a4\u30d7\u306e\u4f5c\u6210\u671f\u9593\u306e\u77ed\u7e2e\u7b49\u5de5\u592b\u3092\u65bd\u3057\u3001\u81e8\u5e8a\u8a66\u9a13\u306e\u77ed\u7e2e\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002<\/p><p>&nbsp;<\/p><p><strong>\uff13\uff0e\uff13\u3000\u8ab2\u984c\u2462\u3000\u82b1\u7c89\u4e0a\u306e\u6297\u539f\u767a\u73fe\u90e8\u4f4d\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb<\/strong><\/p><p><strong>\u3000<\/strong>2.1\u3067\u524d\u8ff0\u3057\u305f\u901a\u308a\u3001\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u306e\u969b\u306b\u3001\u82b1\u7c89\u7279\u7570\u7684\u306b\u8d77\u52d5\u3059\u308b\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u3092\u4e00\u7dd2\u306b\u7d44\u307f\u8fbc\u3080\u3053\u3068\u3067\u3001\u82b1\u7c89\u4e0a\u306b\u4e0d\u6d3b\u5316\u6297\u539f\u3092\u767a\u73fe\u3059\u308b\u3053\u3068\u306f\u53ef\u80fd\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u56f37\u306b\u793a\u3059\u3088\u3046\u306b\u82b1\u7c89\u306f\u6297\u539f\u306e\u7d04300\u500d\u306e\u5f84\u3092\u6301\u3064\u305f\u3081\u3001\u82b1\u7c89\u306e\u7a81\u8d77\u5148\u7aef\u4e0a\u306b\u6297\u539f\u3092\u767a\u73fe\u3055\u305b\u306a\u3051\u308c\u3070\u3001\u82b1\u7c89\u304c\u9f3b\u7c98\u819c\u3084\u54bd\u5589\u982d\u7c98\u819c\u4e0a\u306b\u4ed8\u7740\u3057\u305f\u969b\u3001\u6297\u539f\u304c\u7d30\u80de\u5185\u306b\u53d6\u308a\u8fbc\u307e\u308c\u306a\u3044\u3002\u3088\u3063\u3066\u3001\u82b1\u7c89\u8868\u9762\u306e\u7a81\u8d77\u5148\u7aef\u7279\u7570\u7684\u306b\u6297\u539f\u304c\u767a\u73fe\u3059\u308b\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306e\u6539\u826f\u304c\u5fc5\u8981\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/p><div class=\"fig\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-441\" src=\"http:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f37-300x209.png\" alt=\"\" width=\"300\" height=\"209\" srcset=\"https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f37-300x209.png 300w, https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/\u56f37.png 755w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><div class=\"caption\"><strong>\u56f37. \u5404\u7c92\u5b50\u306e\u30b5\u30a4\u30ba<\/strong><\/div><\/div><p>&nbsp;<\/p><p><strong>\uff13\uff0e\uff14\u3000\u5c55\u671b\u2460\u3000<\/strong><\/p><p>\u3000\u672c\u7a3f\u3067\u306f\u30d2\u30c8\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u96c6\u56e3\u514d\u75ab\u3092\u91b8\u6210\u3059\u308b\u30b7\u30b9\u30c6\u30e0\u306e\u63d0\u6848\u3092\u884c\u3063\u305f\u304c\u3001\u611f\u67d3\u75c7\u306e\u5a92\u4ecb\u5bbf\u4e3b\u3068\u306a\u308b\u8c5a\u3084\u9ce5\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u30b7\u30b9\u30c6\u30e0\u3092\u8a2d\u8a08\u3057\u3001\u8c5a\u3084\u9ce5\u9593\u3067\u306e\u611f\u67d3\u3084\u30a6\u30a3\u30eb\u30b9\u5897\u6b96\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u3001\u7d50\u679c\u3068\u3057\u3066\u30d2\u30c8\u3078\u306e\u611f\u67d3\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3059\u308b\u30b7\u30b9\u30c6\u30e0\u3078\u306e\u5fdc\u7528\u3082\u8003\u3048\u3089\u308c\u308b\u3002<\/p><p>\u307e\u305f\u3001\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306b\u9650\u3089\u305a\u3001\u6bce\u5e74\u611f\u67d3\u306e\u30ea\u30b9\u30af\u304c\u5e38\u5728\u5316\u3057\u3066\u3044\u308b\u611f\u67d3\u75c7\u3067\u3001\u30ef\u30af\u30c1\u30f3\u304c\u78ba\u7acb\u3055\u308c\u305f\u3082\u306e\u3067\u3042\u308c\u3070\u3001\u5fdc\u7528\u304c\u53ef\u80fd\u3068\u8003\u3048\u3089\u308c\u308b\u3002COVID19\u3082\u5c06\u6765\u30ef\u30af\u30c1\u30f3\u304c\u78ba\u7acb\u3055\u308c\u308c\u3070\u3001\u672c\u30b7\u30b9\u30c6\u30e0\u3092\u4f7f\u3063\u3066\u96c6\u56e3\u514d\u75ab\u3092\u91b8\u6210\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/p><p>&nbsp;<\/p><p><strong>\uff14\uff0e\u7d50\u8ad6<\/strong><\/p><p>\u3000\u672c\u7a3f\u3067\u306f\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u306b\u3088\u308a\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306e\u4e0d\u6d3b\u5316\u6297\u539f\u3092\u6728\u3005\u306e\u82b1\u7c89\u4e0a\u306b\u767a\u73fe\u3055\u305b\u3001\u9178\u6027\u96e8\u306b\u3088\u308a\u6539\u5909\u578b\u6297\u539f\u3078\u3068\u5909\u8c8c\u3092\u9042\u3052\u305f\u6297\u539f\u304c\u82b1\u7c89\u3092\u5a92\u4ecb\u3068\u3057\u3066\u4eba\u3005\u306b\u5438\u5165\u3055\u308c\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u65e5\u5e38\u751f\u6d3b\u3092\u9001\u308b\u4e2d\u3067\u7121\u610f\u8b58\u306e\u3046\u3061\u306b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306e\u69d8\u3005\u306a\u4e9c\u578b\u306b\u5bfe\u3059\u308b\u96c6\u56e3\u514d\u75ab\u304c\u91b8\u6210\u3055\u308c\u308b\u30b7\u30b9\u30c6\u30e0\u3092\u63d0\u6848\u3057\u305f\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u56fd\u6c11\u306e\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306b\u5bfe\u3059\u308b\u4e88\u9632\u610f\u8b58\u306b\u5de6\u53f3\u3055\u308c\u308b\u3053\u3068\u306a\u304f\u3001\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306b\u611f\u67d3\u3059\u308b\u30ea\u30b9\u30af\u4f4e\u6e1b\u3068\u8010\u6027\u306e\u5e95\u4e0a\u3052\u3092\u5b9f\u73fe\u3067\u304d\u3001\u7c73\u56fd\u306e\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u611f\u67d3\u8005\u6570\u53ca\u3073\u3001\u6b7b\u8005\u6570\u306e\u4f4e\u6e1b\u306b\u8ca2\u732e\u3067\u304d\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/p><p>&nbsp;<\/p><p><strong>\uff15\uff0e\u53c2\u8003\u6587\u732e<\/strong><\/p><ol><li style=\"list-style-type: none;\"><ol><li>\u6cb3\u5ca1\u7fa9\u88d5, \u5800\u672c\u7814\u5b50\uff1a\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30d1\u30f3\u30c7\u30df\u30c3\u30af. \u8b1b\u8ac7\u793e 42-56<\/li><li>https:\/\/www.cdc.gov\/flu\/fluvaxview\/coverage-1819estimates.htm#:~:text=Flu%20vaccination%20coverage%20among%20adults,than%20the%202016%E2%80%9317%20season. (2020\u5e746\u670827\u65e5)<\/li><li>Tomonori Nochi, Hidenori Takagi, et al: Rice-base mucosal Vaccine as a global strategy for cold-chain- and needle-free accination. Proc Natl Acad Sci USA. 2007 Jun 26; 104(26): 10986-10991.<\/li><li>Mirai Azuma, Reina Morimoto, et al: A petal-speci\ufb01c InMYB1 promoter from Japanese morning glory: a useful tool for molecular breeding of \ufb02oricultural crops. Plant Biotechnology Journal (2016) 14, pp. 354-363<\/li><li>Yu Adachi, Keisuke Tonouchi, et al: Exposure of an occluded hemagglutinin epitope drives selection of a class of cross-protective influenza antibodies. Nature Communications 10, Article number: 3883 (2019)<\/li><\/ol><\/li><\/ol><p>&nbsp;<\/p><p style=\"text-align: right;\">(2021\u5e7410\u670827\u65e5\u53d7\u7406, 2022\u5e741\u670810\u65e5\u516c\u958b)<\/p><hr \/><div class=\"fig\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-442\" src=\"http:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/hattori.takashi-200x300.jpg\" alt=\"\" width=\"200\" height=\"300\" srcset=\"https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/hattori.takashi-200x300.jpg 200w, https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/hattori.takashi-768x1154.jpg 768w, https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/hattori.takashi-682x1024.jpg 682w, https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-content\/uploads\/2021\/10\/hattori.takashi.jpg 1820w\" sizes=\"(max-width: 200px) 100vw, 200px\" \/><\/div><h5><strong>\u670d\u90e8\u3000\u8cb4\u53f8 (\u306f\u3063\u3068\u308a \u305f\u304b\u3057)<\/strong><\/h5><p><strong>\u30bd\u30cb\u30fc\u682a\u5f0f\u4f1a\u793e\u3000\u65b0\u898f\u30d3\u30b8\u30cd\u30b9\u30fb\u6280\u8853\u958b\u767a\u672c\u90e8<\/strong><\/p><p>BMC51\u671f<\/p><p>&nbsp;<\/p><h5><strong>\u7565\u6b74<\/strong><\/h5><p>2004\u5e743\u6708\u3000\u4eac\u90fd\u5927\u5b66\u5927\u5b66\u9662 \u30a8\u30cd\u30eb\u30ae\u30fc\u79d1\u5b66\u7814\u7a76\u79d1 \u30a8\u30cd\u30eb\u30ae\u30fc\u793e\u4f1a\u74b0\u5883\u5b66\u5c02\u653b \u4fee\u58eb\u8ab2\u7a0b\u4fee\u4e86<br \/>2004\u5e744\u6708\u3000\u30bd\u30cb\u30fc\u682a\u5f0f\u4f1a\u793e\u5165\u793e\u3000\u5bb6\u5ead\u7528\u30d3\u30c7\u30aa\u30ab\u30e1\u30e9\u3000\u300c\u30cf\u30f3\u30c7\u30a3\u30ab\u30e0\u300d\u306e\u5546\u54c1\u8a2d\u8a08\u306b\u5f93\u4e8b<br \/>2018\u5e7410\u6708\u3000\u30bd\u30cb\u30fc\u30fb\u30aa\u30ea\u30f3\u30d1\u30b9\u30e1\u30c7\u30a3\u30ab\u30eb\u30bd\u30ea\u30e5\u30fc\u30b7\u30e7\u30f3\u30ba\u682a\u5f0f\u4f1a\u793e(\u51fa\u5411)\u3000\u65b0\u898f\u4e8b\u696d\u4f01\u753b\u5ba4\u306b\u6240\u5c5e<br \/>2021\u5e74 5\u6708\u3000\u30bd\u30cb\u30fc\u682a\u5f0f\u4f1a\u793e \u65b0\u898f\u30d3\u30b8\u30cd\u30b9\u30fb\u6280\u8853\u958b\u767a\u672c\u90e8\u306b\u7570\u52d5<\/p><p>&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"\uff11\uff0e\u80cc\u666f\uff11\uff0e\uff11\uff0e\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a3\u30eb\u30b9\u306e\u8105\u5a01\u3000\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306b\u611f\u67d3\u3059\u308b\u3068\u6570\u65e5\u7a0b\u5ea6\u306e\u6f5c\u4f0f\u671f\u9593\u3092\u7d4c\u3066\u767a\u75c7\u3057\u300138\u5ea6\u4ee5\u4e0a\u306e\u9ad8\u71b1\u3001\u982d\u75db\u3001\u5168\u8eab\u306e\u5026\u6020\u611f\u3001\u7b4b\u8089\u75db\u30fb\u95a2\u7bc0\u75db\u3084\u54b3\u30fb\u9f3b\u6c41\u306a\u3069\u306e\u75c7\u72b6\u304c\u73fe\u308c\u308b\u3002\u5b63\u7bc0\u6027\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u3067\u3042\u308c\u3070\u901a\u5e381 [&hellip;]","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5],"class_list":["post-434","post","type-post","status-publish","hentry","category-5"],"_links":{"self":[{"href":"https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-json\/wp\/v2\/posts\/434"}],"collection":[{"href":"https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-json\/wp\/v2\/comments?post=434"}],"version-history":[{"count":0,"href":"https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-json\/wp\/v2\/posts\/434\/revisions"}],"wp:attachment":[{"href":"https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-json\/wp\/v2\/media?parent=434"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/twins.twmu.ac.jp\/SFM\/journal\/wp-json\/wp\/v2\/categories?post=434"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}